hydrochlorothiazide

komponim kimik

External resources

numri CAS
MeSH descriptor ID
D006852

referuar si: Hydrochlorothiazide

MeSH concept ID
NSC number
ChEMBL ID
Gran Enciclopèdia Catalana ID
Human Metabolome Database ID
MeSH tree code
ECHA Substance Infocard ID
PDB structure ID
DrugCentral ID
Probes And Drugs ID
NDF-RT ID
Freebase ID
Reaxys registry number
625101[11]
PubChem CID
UniChem compound ID
Quora topic ID
PDB ligand ID
SPLASH
KEGG ID
OpenAlex ID
KBpedia ID
InChIKey
DrugBank ID
Gran Enciclopèdia Catalana ID (former scheme)
WikiProjectMed ID
UNII
HSDB ID
SureChEMBL ID
kodi ATC
Microsoft Academic ID
DSSTOX compound identifier
InChI
WordNet 3.1 Synset ID
03557349-n[19]
Guide to Pharmacology Ligand ID
ChEBI ID
5778[3][21]

mapping relation type: përputhje e përpiktë

UMLS CUI
CAB ID
DSSTox substance ID
ChemSpider ID
numri CE
MedlinePlus drug identifier
World Health Organisation international non-proprietary name numeric ID
MassBank accession ID
CAMEO Chemicals ID
RxNorm ID

instancë e

type of chemical entity

nënklasë e

thiazide[26]

përdor

strukturë kimike

image of molecular model or crystal lattice model

përshkruan: space-filling model

masa

296,964 dalton[27]

formula kimike

C₇H₈ClN₃O₄S₂[12]

kanonikja SMILES

C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl[12]

melting point

269 Celcius[28]

defined daily dose

25 milligram[29]

route of administration: oral administration

active ingredient in

Microzide[30]

World Health Organisation international non-proprietary name

hydrochlorothiazide[11][31]

medical condition treated

anasarka[32]
nephrotic syndrome[32]
congestive heart failure[32]
nephrogenic diabetes insipidus[34][35]

significant drug interaction

desmopressin[36]

side effect: hyponatremia

carbamazepin[37]

side effect: hyponatremia

dronedarone[36]

side effect: Achor-Smith syndrom

triamcinolone[36]

side effect: Achor-Smith syndrom

methylprednisolone[36]

side effect: Achor-Smith syndrom

prednisone[36]

side effect: Achor-Smith syndrom

fludrocortisone[36]

side effect: Achor-Smith syndrom

Kortizoli[36]

side effect: Achor-Smith syndrom

prednisolone[36]

side effect: Achor-Smith syndrom

droperidol[36]

side effect: Achor-Smith syndrom

arsenic trioxide[36]

side effect: Achor-Smith syndrom

sotalol[37]

side effect: Achor-Smith syndrom

litiumi[36]

side effect: Achor-Smith syndrom

Aspirina[37]

side effect: acute kidney injury

nabumetone[37]

side effect: hyponatremia

naproxen[37]

side effect: hyponatremia

celecoxib[37]

side effect: hyponatremia

Diklofenaku[37]

side effect: hyponatremia

piroxicam[37]

side effect: hyponatremia

meloxicam[37]

side effect: hyponatremia

(RS)-fenoprofen[37]

side effect: hyponatremia

(+-)-flurbiprofen[37]

side effect: hyponatremia

ibuprofen[37]

side effect: hyponatremia

indomethacin[37]

side effect: hyponatremia

(RS)-ketoprofen[37]

side effect: hyponatremia

(RS)-etodolac[37]

side effect: hyponatremia

sulindac[37]

side effect: hyponatremia

parecoxib[37]

side effect: hyponatremia

aceclofenac[37]

side effect: hyponatremia

tenoxicam[37]

side effect: hyponatremia

nabumetone[37]

side effect: acute kidney injury

naproxen[37]

side effect: acute kidney injury

celecoxib[37]

side effect: acute kidney injury

Diklofenaku[37]

side effect: acute kidney injury

piroxicam[37]

side effect: acute kidney injury

meloxicam[37]

side effect: acute kidney injury

(RS)-fenoprofen[37]

side effect: acute kidney injury

(+-)-flurbiprofen[37]

side effect: acute kidney injury

ibuprofen[37]

side effect: acute kidney injury

indomethacin[37]

side effect: acute kidney injury

(RS)-ketoprofen[37]

side effect: acute kidney injury

(RS)-etodolac[37]

side effect: acute kidney injury

sulindac[37]

side effect: acute kidney injury

parecoxib[37]

side effect: acute kidney injury

aceclofenac[37]

side effect: acute kidney injury

tenoxicam[37]

side effect: acute kidney injury

bromocriptine[36]

side effect: Hipotensioni

droperidol[36]

side effect: Hipotensioni

lisinopril dihydrate[36]

side effect: Hipotensioni

quinapril[36]

side effect: Hipotensioni

ramipril[36]

side effect: Hipotensioni

captopril[36]

side effect: Hipotensioni

enalapril[36]

side effect: Hipotensioni

trandolapril[36]

side effect: Hipotensioni

fosinopril[36]

side effect: Hipotensioni

sotalol[37]

side effect: Hipotensioni

perindopril[36]

side effect: Hipotensioni

droperidol[36]

side effect: torsades de pointes

droperidol[36]

side effect: long QT syndrome

droperidol[36]

side effect: pulseless electrical activity

droperidol[36]

side effect: cardiotoxicity

sotalol[37]

side effect: torsades de pointes

sotalol[37]

side effect: long QT syndrome

sotalol[37]

side effect: pulseless electrical activity

sotalol[37]

side effect: cardiotoxicity

Aspirina[37]

side effect: nephrotoxicity

nabumetone[37]

side effect: nephrotoxicity

naproxen[37]

side effect: nephrotoxicity

celecoxib[37]

side effect: nephrotoxicity

Diklofenaku[37]

side effect: nephrotoxicity

piroxicam[37]

side effect: nephrotoxicity

meloxicam[37]

side effect: nephrotoxicity

(RS)-fenoprofen[37]

side effect: nephrotoxicity

(+-)-flurbiprofen[37]

side effect: nephrotoxicity

ibuprofen[37]

side effect: nephrotoxicity

indomethacin[37]

side effect: nephrotoxicity

(RS)-ketoprofen[37]

side effect: nephrotoxicity

(RS)-etodolac[37]

side effect: nephrotoxicity

sulindac[37]

side effect: nephrotoxicity

parecoxib[37]

side effect: nephrotoxicity

aceclofenac[37]

side effect: nephrotoxicity

tenoxicam[37]

side effect: nephrotoxicity

lisinopril dihydrate[36]

side effect: decreased blood pressure

quinapril[36]

side effect: decreased blood pressure

ramipril[36]

side effect: decreased blood pressure

captopril[36]

side effect: decreased blood pressure

enalapril[36]

side effect: decreased blood pressure

trandolapril[36]

side effect: decreased blood pressure

fosinopril[36]

side effect: decreased blood pressure

perindopril[36]

side effect: decreased blood pressure

digoxin[38]

side effect: heart arrhythmia

digoxin[38]

side effect: vjellja

digoxin[38]

side effect: nausea

digoxin[38]

side effect: Toksiciteti

arsenic trioxide[36]

side effect: torsades de pointes

arsenic trioxide[36]

side effect: long QT syndrome

dronedarone[36]

side effect: hypomagnesemia

bromocriptine[36]

side effect: Hiperglikemia

bromocriptine[36]

side effect: increased insulin requirement

triamcinolone[36]

side effect: heart arrhythmia

methylprednisolone[36]

side effect: heart arrhythmia

prednisone[36]

side effect: heart arrhythmia

fludrocortisone[36]

side effect: heart arrhythmia

Kortizoli[36]

side effect: heart arrhythmia

reagon fizikisht me

solute carrier family 12 member 3[39]

subjekti ka rol: Frenuesi i enzimës

boxed warning[40]

subjekti ka rol

antihypertensive drug[41]
diuretic[41]
Sodium Chloride Symporter Inhibitors[41]
essential medicine

stylized name

hydroCHLOROthiazide[42]

lëshuar nga: Institute for Safe Medication Practices

ka veçori: Tall Man lettering

kategoria në Commons

Hydrochlorothiazide

Reference

  1. ^ a b c d e f Global Substance Registration System, 19 nëntor 2016, anglisht, hydrochlorothiazide, 0J48LPH2TH
  2. ^ CAS Common Chemistry, 9 prill 2021, https://commonchemistry.cas.org/detail?cas_rn=58-93-5, JZUFKLXOESDKRF-UHFFFAOYSA-N
  3. ^ a b ChEMBL, 19 nëntor 2016, anglisht, HYDROCHLOROTHIAZIDE, CHEMBL435
  4. ^ a b inferred from InChIKey
  5. ^ a b c d e f JZUFKLXOESDKRF-UHFFFAOYSA-N, InChIKey
  6. ^ ECHA Substance Infocard database, 27 dhjetor 2018, 100.000.367, Hydrochlorothiazide, CAS no.: 58-93-5
  7. ^ Protein Data Bank, 19 tetor 2016, anglisht, 3IK6, 3IK6
  8. ^ Protein Data Bank, 19 tetor 2016, anglisht, 3IJX, 3IJX
  9. ^ a b UniChem
  10. ^ Freebase Data Dumps, 28 tetor 2013
  11. ^ a b c d ChEBI, 19 tetor 2016, anglisht, hydrochlorothiazide, 5778
  12. ^ a b c d e PubChem, 19 nëntor 2016, anglisht, 3639, hydrochlorothiazide
  13. ^ Quora
  14. ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  15. ^ KBpedia, 9 korrik 2020
  16. ^ ChEBI release 2020-09-01
  17. ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, Hydrochlorothiazide, 3096
  18. ^ DrugBank, anglisht, 17 nëntor 2015, 00999, Hydrochlorothiazide
  19. ^ GF WordNet
  20. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 19 nëntor 2016, anglisht, 4836, hydrochlorothiazide
  21. ^ InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13), International Chemical Identifier
  22. ^ CAB Thesaurus, 6 prill 2020
  23. ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  24. ^ ChemSpider, 19 nëntor 2016, anglisht, 3513, Hydrochlorothiazide
  25. ^ https://mednet-communities.net/inn/db/ViewINN.aspx?i=841
  26. ^ N0000145995, 27 shkurt 2018, NDF-RT
  27. ^ PubChem, 19 tetor 2016, anglisht, 3639, hydrochlorothiazide
  28. ^ Jean-Claude Bradley Open Melting Point Dataset
  29. ^ https://www.whocc.no/atc_ddd_index/?code=C03AA03
  30. ^ RxNorm, 218369, 14 shkurt 2018
  31. ^ Recommended INN: List 4, 1962
  32. ^ a b c d N0000145995, 13 dhjetor 2016, anglisht, NDF-RT
  33. ^ Drug Indications Extracted from FAERS, 2 tetor 2018
  34. ^ 24352504
  35. ^ MEDLINE, https://medlineplus.gov/druginfo/meds/a682571.html
  36. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq A reference set of clinically relevant adverse drug-drug interactions, hypothetically
  37. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be A reference set of clinically relevant adverse drug-drug interactions, probably
  38. ^ a b c d A reference set of clinically relevant adverse drug-drug interactions, established
  39. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 4836, anglisht
  40. ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  41. ^ a b c Medical Subject Headings, 15 mars 2018, D006852
  42. ^ 2 shtator 2022, https://www.ismp.org/recommendations/tall-man-letters-list