Flucloxacillin

Flucloxacillin ose floxacillin është një antibiotik kundër baktereve Gram-pozitive.

Flucloxacillin

Clinical data
Pregnancy category	AU: B1
Routes of administration	Oral, IM, IV, intrapleural, intraarticular
ATC code	J01CF05 (WHO) QJ51CF05
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability	50–70%
Metabolism	Hepatic
Elimination half-life	0.75–1 hour
Excretion	Renal
Identifiers
IUPAC name (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number	5250-39-5
PubChem CID	21319
DrugBank	APRD00609
ChemSpider	20037
UNII	43B2M34G2V
KEGG	D04196
ChEMBL	ChEMBL222645
CompTox Dashboard (EPA)	DTXSID8023056
ECHA InfoCard	100.023.683
Chemical and physical data
Formula	C19H17ClFN3O5S
Molar mass	453.87 g/mol g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(O)[C@@H]3N4C(=O)[C@@H](NC(=O)c2c(onc2c1c(F)cccc1Cl)C)[C@H]4SC3(C)C
InChI InChI=1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1Stampa:Stdinchicite Key:UIOFUWFRIANQPC-JKIFEVAISA-NStampa:Stdinchicite
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