fentanyl

komponim kimik

External resources

MeSH descriptor ID
D005283

referuar si: Fentanyl

Encyclopædia Britannica Online ID
science/fentanyl

referuar si: fentanyl

LiverTox ID
ChEMBL ID
BBC Things ID
Human Metabolome Database ID
MeSH tree code
WikiKids ID
ECHA Substance Infocard ID
DrugCentral ID
Encyclopedia of China (Third Edition) ID
141489

referuar si: 芬太尼

Probes And Drugs ID
NDF-RT ID
Freebase ID
Reaxys registry number
494484[9]
PubChem CID
UniChem compound ID
YSO ID
PDB ligand ID
SPLASH
KEGG ID
kodi ATC
Merck Index monograph
OpenAlex ID
InChI
InChIKey
DrugBank ID
ChEBI ID
119915[1][15]

mapping relation type: përputhje e përpiktë

DSSTox substance ID
WikiProjectMed ID
KBpedia ID
IEDB Epitope ID
SureChEMBL ID
UNII
electronic Essential Medicines List medicine ID
DeCS ID
Microsoft Academic ID
MedlinePlus drug identifier
a605043

route of administration: oral administration

a612015

route of administration: nasal administration

a613041

route of administration: sublingual administration

a601202

route of administration: transdermal administration

Store medisinske leksikon ID
DSSTOX compound identifier
UMLS CUI
UK Parliament thesaurus ID
438805

referuar si: Fentanyl

numri CAS
ChemSpider ID
numri CE
Guide to Pharmacology Ligand ID
Treccani's Dizionario di Medicina ID
fentanyl

referuar si: Fentanyl

data e publikimit: 2010

BBC News topic ID
MassBank accession ID
ScienceDirect topic ID
RxNorm ID
HSDB ID

instancë e

type of chemical entity

nënklasë e

phenethylamine
piperidine
N,N-disubstituted primary carboxamide

përdor

strukturë kimike

image of molecular model or crystal lattice model

përshkruan: ball-and-stick model

përshkruan: space-filling model

masa

336,220164 dalton[23]

associated hazard

fentanyl toxicity

shkak i

fentanyl toxicity

zbulues

Paul Janssen

data: 1960

formula kimike

C₂₂H₂₈N₂O[10]

kanonikja SMILES

CCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3[10]

melting point

83±1 Celcius[24]

safety classification and labelling

NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response[25]

NFPA Special: s’ka vlerë

NFPA Health: 4

NFPA Fire: 1

NFPA Instability: 0

median lethal dose (LD50)

3,1 milligram per kilogram

route of administration: vlerë e panjohur

applies to taxon: laboratory rat

0,03 milligram per kilogram

route of administration: vlerë e panjohur

applies to taxon: majmuni

active ingredient in

Effentora[26]
Pecfent[27]
Fentora[28]
Abstral[29]
Ionsys[30]
Duragesic[31]
Lazanda[32]
Actiq[33]
Subsys[34]

World Health Organisation international non-proprietary name

fentanyl[9]

medical condition treated

osteoarthritis susceptibility 1[36]
complex regional pain syndrome[36]
peripheral neuropathy[36]

significant drug interaction

isocarboxazid[37]
phenelzine[37]
procarbazine[37]
(±)-deprenyl[37]
amiodarone[38]
(RS)-methadone[39]

side effect: sinus bradycardia

remifentanil[39]

side effect: sinus bradycardia

alfentanil[39]

side effect: sinus bradycardia

sufentanil[39]

side effect: sinus bradycardia

pethidine[39]

side effect: depressed level of consciousness

pethidine[39]

side effect: central respiratory depression

tramadol[39]

side effect: depressed level of consciousness

tramadol[39]

side effect: central respiratory depression

(RS)-methadone[39]

side effect: depressed level of consciousness

(RS)-methadone[39]

side effect: central respiratory depression

Morfina[39]

side effect: depressed level of consciousness

Morfina[39]

side effect: central respiratory depression

oxycodone[39]

side effect: depressed level of consciousness

oxycodone[39]

side effect: central respiratory depression

hydromorphone[39]

side effect: depressed level of consciousness

hydromorphone[39]

side effect: central respiratory depression

dihydrocodeine[39]

side effect: depressed level of consciousness

dihydrocodeine[39]

side effect: central respiratory depression

Kodeina[39]

side effect: depressed level of consciousness

Kodeina[39]

side effect: central respiratory depression

remifentanil[39]

side effect: depressed level of consciousness

remifentanil[39]

side effect: central respiratory depression

tapentadol[39]

side effect: depressed level of consciousness

tapentadol[39]

side effect: central respiratory depression

alfentanil[39]

side effect: depressed level of consciousness

alfentanil[39]

side effect: central respiratory depression

sufentanil[39]

side effect: depressed level of consciousness

sufentanil[39]

side effect: central respiratory depression

(±)-promethazine[39]

side effect: paralytic ileus

(±)-promethazine[39]

side effect: depressed level of consciousness

(±)-promethazine[39]

side effect: central respiratory depression

pimozide[39]

side effect: paralytic ileus

pimozide[39]

side effect: depressed level of consciousness

pimozide[39]

side effect: central respiratory depression

fluphenazine[39]

side effect: paralytic ileus

fluphenazine[39]

side effect: depressed level of consciousness

fluphenazine[39]

side effect: central respiratory depression

(RS)-hydroxyzine[39]

side effect: paralytic ileus

(RS)-hydroxyzine[39]

side effect: depressed level of consciousness

(RS)-hydroxyzine[39]

side effect: central respiratory depression

olanzapine[39]

side effect: paralytic ileus

olanzapine[39]

side effect: depressed level of consciousness

olanzapine[39]

side effect: central respiratory depression

loxapine[39]

side effect: paralytic ileus

loxapine[39]

side effect: depressed level of consciousness

loxapine[39]

side effect: central respiratory depression

Klorpromazina[39]

side effect: paralytic ileus

Klorpromazina[39]

side effect: depressed level of consciousness

Klorpromazina[39]

side effect: central respiratory depression

chlorpheniramine[39]

side effect: paralytic ileus

imipramine[39]

side effect: paralytic ileus

clomipramine[39]

side effect: paralytic ileus

itraconazole[39]

side effect: depressed level of consciousness

itraconazole[39]

side effect: central respiratory depression

levomepromazine[39]

side effect: depressed level of consciousness

trimeprazine[39]

side effect: depressed level of consciousness

nitrazepam[39]

side effect: depressed level of consciousness

zopiclone[39]

side effect: depressed level of consciousness

clobazam[39]

side effect: depressed level of consciousness

periciazine[39]

side effect: depressed level of consciousness

dexmedetomidine[39]

side effect: depressed level of consciousness

(RS)-sulpiride[39]

side effect: depressed level of consciousness

perampanel[39]

side effect: depressed level of consciousness

(±)-thiopental[39]

side effect: depressed level of consciousness

midazolam[39]

side effect: depressed level of consciousness

(RS)-baclofen[39]

side effect: depressed level of consciousness

diazepam[39]

side effect: depressed level of consciousness

oxazepam[39]

side effect: depressed level of consciousness

droperidol[39]

side effect: depressed level of consciousness

zolpidem[39]

side effect: depressed level of consciousness

flurazepam[39]

side effect: depressed level of consciousness

aripiprazole[39]

side effect: depressed level of consciousness

haloperidol[39]

side effect: depressed level of consciousness

quetiapine[39]

side effect: depressed level of consciousness

sodium oxybate[39]

side effect: depressed level of consciousness

alprazolam[39]

side effect: depressed level of consciousness

lorazepam[39]

side effect: depressed level of consciousness

clonazepam[39]

side effect: depressed level of consciousness

Clozapina[39]

side effect: depressed level of consciousness

chlordiazepoxide[39]

side effect: depressed level of consciousness

phenobarbital[39]

side effect: depressed level of consciousness

primidone[39]

side effect: depressed level of consciousness

reagon fizikisht me

Opioid receptor delta 1[40]

subjekti ka rol: agonist

opioid receptor kappa 1[40]

subjekti ka rol: agonist

opioid receptor mu 1[40]

subjekti ka rol: agonist

boxed warning[41]

pregnancy category

Australian pregnancy category C
US pregnancy category C

LiverTox likelihood score

LiverTox toxicity likelihood category E[42]

përshkruar nga burimi

Opium Law

subjekti ka rol

opioid receptor agonist[43]
opioid[44]
narcotic[44]
anesthesia adjuvants[44]
intravenous anesthetics[44]
controlled substance
essential medicine

stylized name

fentaNYL[45]

lëshuar nga: Institute for Safe Medication Practices

ka veçori: Tall Man lettering

MCN code

2933.33.63

kategoria në Commons

Fentanyl

kategoria kryesore

Category:Fentanyl

Reference

  1. ^ a b ChEMBL, 19 nëntor 2016, anglisht, FENTANYL, CHEMBL596
  2. ^ BBC Things
  3. ^ a b inferred from InChIKey
  4. ^ a b c d e f PJMPHNIQZUBGLI-UHFFFAOYSA-N, InChIKey
  5. ^ ECHA Substance Infocard database, 27 dhjetor 2018, 100.006.468, Fentanyl, CAS no.: 437-38-7
  6. ^ a b UniChem
  7. ^ a b c d e Global Substance Registration System, 19 nëntor 2016, anglisht, fentanyl, UF599785JZ
  8. ^ Freebase Data Dumps, 28 tetor 2013
  9. ^ a b c ChEBI, 3 tetor 2016, anglisht, fentanyl, 119915
  10. ^ a b c d e PubChem, 19 nëntor 2016, anglisht, 3345, fentanyl
  11. ^ YSO-Wikidata mapping project
  12. ^ a b DrugBank, anglisht, 17 nëntor 2015, 00813, Fentanyl
  13. ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  14. ^ ChEBI release 2020-09-01
  15. ^ InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3, International Chemical Identifier
  16. ^ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
  17. ^ KBpedia, 9 korrik 2020
  18. ^ Immune Epitope Database and Analysis Resource, 1 mars 2022, 153507
  19. ^ CAS Common Chemistry, 6 prill 2021, PJMPHNIQZUBGLI-UHFFFAOYSA-N, https://commonchemistry.cas.org/detail?cas_rn=437-38-7
  20. ^ ChemSpider, 19 nëntor 2016, anglisht, 3228, Fentanyl
  21. ^ IUPHAR/BPS Guide to PHARMACOLOGY, 19 nëntor 2016, anglisht, 1626, fentanyl
  22. ^ Hazardous Substances Data Bank, 10 maj 2021, 28 tetor 2019, Fentanyl, 3329
  23. ^ PubChem, 3 tetor 2016, anglisht, 3345, fentanyl
  24. ^ http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750022.html
  25. ^ 5 maj 2018, https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750022.html
  26. ^ http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000833/human_med_000754.jsp, 22 mars 2017, EMEA/H/C/000833
  27. ^ http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001164/human_med_001387.jsp, 22 mars 2017, EMEA/H/C/001164
  28. ^ RxNorm, 668619, 14 shkurt 2018
  29. ^ RxNorm, 1053648, 14 shkurt 2018
  30. ^ RxNorm, 1666832, 14 shkurt 2018
  31. ^ RxNorm, 151678, 14 shkurt 2018
  32. ^ RxNorm, 1115547, 14 shkurt 2018
  33. ^ RxNorm, 215008, 14 shkurt 2018
  34. ^ RxNorm, 1237051, 14 shkurt 2018
  35. ^ N0000147049, 13 dhjetor 2016, anglisht, NDF-RT
  36. ^ a b c d e f Drug Indications Extracted from FAERS, 2 tetor 2018
  37. ^ a b c d High-priority drug–drug interactions for use in electronic health records
  38. ^ 10.3389/FPHAR.2018.01145
  39. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd A reference set of clinically relevant adverse drug-drug interactions, hypothetically
  40. ^ a b c IUPHAR/BPS Guide to PHARMACOLOGY, 17 gusht 2016, 1626, anglisht
  41. ^ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  42. ^ LiverTox, 8 prill 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/FentanylAndAnalogues, 25 prill 2019
  43. ^ N0000147049, 5 mars 2018, NDF-RT
  44. ^ a b c d Medical Subject Headings, 15 mars 2018, D005283
  45. ^ 2 shtator 2022, https://www.ismp.org/recommendations/tall-man-letters-list