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Squalene epoxidase

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proteinë

External resources

numri CAS
9029-62-3
RefSeq Protein ID
NP_003120[1]
XP_011515548[1]
MeSH tree code
D08.811.682.690.708.749
UMLS CUI
C0075086[2]
Ensembl protein ID
ENSP00000265896[3]
ENSP00000428239[4]
ENSP00000429916[5]
ENSP00000430331[6]
UniProt protein ID
Q14534[7]
MeSH descriptor ID
D050603

referuar si: Squalene Monooxygenase

Microsoft Academic ID
85411794
OpenAlex ID
C85411794[8]
Freebase ID
/m/02qtn98[9]

instancë e

proteinë[7]

found in taxon

Homo sapiens[7]

encoded by

SQLE[7]

molecular function

oxidoreductase activity[10]

metoda e përcaktimit: IEA

flavin adenine dinucleotide binding[11]

metoda e përcaktimit: IEA

squalene monooxygenase activity[12][13][14][15][16]

metoda e përcaktimit: IBA, IEA, NAS, TAS

squalene monooxygenase activity[17][18][19][20]

metoda e përcaktimit: IBA, IEA, NAS

squalene monooxygenase activity[21][11][22][23][24]

metoda e përcaktimit: IBA, IDA, IEA, NAS

FAD binding[23]

metoda e përcaktimit: IDA

cell component

organelle membrane[10]

metoda e përcaktimit: IEA

integral component of membrane[25][18]

metoda e përcaktimit: IEA

endoplasmic reticulum membrane[26][10]

metoda e përcaktimit: TAS, IEA

membrane[10]

metoda e përcaktimit: IEA

intracellular membrane-bounded organelle[25][19]

metoda e përcaktimit: IEA

endoplasmic reticulum[10][24]

metoda e përcaktimit: IBA, IEA

integral component of membrane[10][11][23]

metoda e përcaktimit: IDA, IEA

intracellular membrane-bounded organelle[10][22][23]

metoda e përcaktimit: IDA, IEA

biological process

cellular aromatic compound metabolic process[22]

metoda e përcaktimit: IEA

cholesterol biosynthetic process[26]

metoda e përcaktimit: TAS

response to organic substance[22]

metoda e përcaktimit: IEA

cholesterol metabolic process[22][24]

metoda e përcaktimit: IBA, IEA

sterol biosynthetic process[27][28]

metoda e përcaktimit: IBA, NAS

regulation of cholesterol biosynthetic process[26]

metoda e përcaktimit: TAS

sterol biosynthetic process[17][18][20]

metoda e përcaktimit: IBA, IEA, NAS

sterol biosynthetic process[21][11][23][24]

metoda e përcaktimit: IBA, IDA, IEA, NAS

përputhje e saktë

http://purl.uniprot.org/uniprot/Q14534[29]

Reference

  1. ^ a b NCBI Gene, 30 maj 2020, 6713
  2. ^ UMLS 2023, 25 maj 2023, inferred by common MeSH mappings on source and on Wikidata
  3. ^ Ensembl Release 99, ENSP00000265896
  4. ^ Ensembl Release 99, ENSP00000428239
  5. ^ Ensembl Release 99, ENSP00000429916
  6. ^ Ensembl Release 99, ENSP00000430331
  7. ^ a b c d UniProt, 13 nëntor 2019, Q14534
  8. ^ OpenAlex, 26 janar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  9. ^ Freebase Data Dumps, 28 tetor 2013
  10. ^ a b c d e f g IEA, 8 prill 2019, Q14534, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, UniProt
  11. ^ a b c d IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 8 prill 2019, InterPro, GOA
  12. ^ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, 7 nëntor 2018, Reactome, GOA
  13. ^ NAS, 7 nëntor 2018, Q14534, Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, UniProt
  14. ^ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, 7 nëntor 2018, InterPro, GOA
  15. ^ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, 7 nëntor 2018, Ensembl genome database project, GOA
  16. ^ IBA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, 7 nëntor 2018, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  17. ^ a b NAS, 1 janar 2018, Q14534, Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, UniProt
  18. ^ a b c IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 1 janar 2018, InterPro, GOA
  19. ^ a b IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 1 janar 2018, Ensembl genome database project, GOA
  20. ^ a b IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 1 janar 2018, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  21. ^ a b NAS, 8 prill 2019, Q14534, Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, UniProt
  22. ^ a b c d e IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 8 prill 2019, Ensembl genome database project, GOA
  23. ^ a b c d e IDA, 8 prill 2019, Q14534, Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, UniProt
  24. ^ a b c d IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 8 prill 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  25. ^ a b IEA, 1 janar 2018, Q14534, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, UniProt
  26. ^ a b c TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14534, 8 prill 2019, Reactome, GOA
  27. ^ NAS, 10 shtator 2018, Q14534, Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, UniProt
  28. ^ IBA, http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14534&geneProductId=UniProtKB:Q14534, 10 shtator 2018, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
  29. ^ Identifiers.org
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